Single Agent Dexamethasone
Dexamethasone is a corticosteroid. Corticosteroids, as single agents, are recommended as an antiemetic regimen in low-emetogenic chemotherapy (LEC) and have been examined for effect on fatigue.
Silver Sulfadiazine
Silver sulfadiazine is an antibacterial agent that has been used as a topical cream on burns. Silver sulfadiazine has been studied for its effect in patients with cancer for radiodermatitis.
Silver Leaf Dressings
Silver is known to have antimicrobial effects, and silver leaf nylon dressing has been shown to enhance healing with burns and skin grafts, as well as have anti-infective properties. Use of silver leaf nylon dressing was evaluated in patients with cancer for the treatment of radiodermatitis.
Silver Impregnated Dressing
Dressings containing ionic silver for surgical wounds have been examined in patients with cancer for effects on the incidence of surgical site infections.
Sertraline
Sertraline is in the selective serotonin reuptake inhibitors (SSRIs) class of antidepressants. It works by increasing the amounts of serotonin in the brain. Sertraline has been examined as an intervention for depression, hot flashes, and fatigue in patients with cancer.
Serotonin 5HT3 Receptor Antagonists (5HT3)
5-hydroxytryptamine (5HT3) receptor antagonists are a class of antiemetic drug used to relieve nausea and vomiting associated with chemotherapy. At this time, four 5HT3 receptor antagonists are approved by the U.S. Food and Drug Administration, ondansetron, granisetron, dolasetron, and palonosetron. There is limited evidence that palonosetron may have a greater efficacy in the prevention of delayed chemotherapy-induced nausea and vomiting.
Selenium
Selenium is an essential mineral found in soil, brazil nuts, fish, and other seafood, poultry, and whole grains. The recommended daily dose is 55 micrograms (mcg) for adults and 60—70 mcg for pregnant or breastfeeding women. Selenium is thought to help preserve elasticity in body tissues, slow aging, improve oxygenation to the heart, and help prevent blood clotting. Selenium was evaluated in patients with cancer for treatment of mucositis.
Scrambler Therapy
Scrambler therapy is a noninvasive approach that uses surface electrostimulation on dermatomes to "scramble" the transmission of pain messages to the brain. Scrambler therapy has been examined in patients with cancer for its effect on neuropathic pain and neuropathy symptoms.
Samital® Mouth Rinse
Samital® is a combination of botanical extracts from bilberry, macleaya cordata fruits, and Echinaceas angustifolia roots. These extracts have antifungal, antiviral, analgesic, and antinflammatory properties, as well as activity to protect mucosa and improve fibroblast proliferation. This solution was examined for its effect in prevention and management of oral mucositis.
Salvia Officinalis
This plant is commonly known as kitchen or common sage, and its extract can be used in tablet form as an herbal remedy. Though the mechanism of action of the extract is still unknown, the primary biologically active agent of sage is thought to be the plant's essential oil. The extract reportedly has anti-inflammatory, antihydrotic, antibiotic, hypoglycemic, estrogenic, astringent, and antispasmodic properties.