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Thrombopoietin

Thrombopoietin is a hormone that stimulates the production and differentiation of bone marrow cells, which produce platelets.

Topical Menthol

Menthol is an organic compound made synthetically or obtained from mint oils. Topical creams containing menthol have been used for relief of minor pain and as a topical analgesic. Menthol appears to activate a channel involved in regulation of sensory neuropathic pain, and has been examined for its effects as a topical agent on painful chemotherapy-induced peripheral neuropathy.

Topical Steroid for Pruritus

Steroids are a type of compound that contains a characteristic chemical structure. Steroid drugs have anti-inflammatory activity. Topical steroids have been examined for effectiveness in the management of skin reactions and pruritus that may occur as part of skin reactions. Steroids applied topically can be absorbed and have systemic effects. The amount absorbed depends on the frequency and duration of application, the strength of the steroid preparation, the amount applied, and the application surface.

Benzodiazepine for Anticipatory Chemotherapy-Induced Nausea and Vomiting

Anticipatory chemotherapy-induced nausea and vomiting is the experience of these symptoms prior to chemotherapy treatment because of the expectation of nausea and vomiting. Benzodiazepines are a class of tranquilizers commonly used to treat a range of conditions, such as anxiety.

Laughter Therapy

Laughter therapy uses humor to help people cope with stress and symptoms and improve their sense of well-being. It may include laughter exercises, clowns, comedy movies, books, games, or puzzles. Laughter promotes the release of endorphins, increases blood oxygenation, and may have anti-inflammatory effects.

Wobe-Mugos E/Proteolytic Enzyme Mixture

Proteolytic enzymes are comprised of papain (100 mg), trypsin (40 mg), and chymotrypsin (40 mg). Proteolytic enzymes break down proteins throughout the body for various metabolic processes and can act as anti-inflammatory agents. This product has been evaluated as an intervention for mucositis and radiodermatitis in patients with cancer.

Infliximab for Unresolved or Refractory Diarrhea

Infliximab is a monoclonal antibody against tumor necrosis factor that has been used to treat autoimmune diseases. Infliximab has been used to treat severe diarrhea related to immunotherapy in patients whose symptoms are not resolved with high-dose steroids.

View Intervention Evaluation Table

Infliximab for Refractory Immunotherapy-Related Dyspnea from Pneumonitis

Infliximab is a monoclonal antibody that works against tumor necrosis factor that has been used to treat autoimmune diseases. Consideration of infliximab administration has been suggested for patients with immunotherapy-related pneumonitis that is unresponsive to systemic steroids.

Hyperbaric Oxygen Therapy

Hyperbaric oxygen therapy is the provision of oxygen which is at a pressure level higher than atmospheric pressure.  The patient in placed in a pressure chamber breathing high concentration of oxygen.  This results in hyperoxygenation of the blood and has been associated with improved wound healing.  Hyperbaric oxygen therapy was evaluated in patients with cancer for treatment of lymphedema.

Hydrosorb

Hydrosorb is a transparent gel dressing that has a high water content.

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