Calcium Channel Blockers
Calcium channel blockers are medications commonly used to treat high blood pressure. The potential effect of these medications on development of chemotherapy-induced peripheral neuropathy was studied.
Calcium and Magnesium Infusion
The infusion of calcium and magnesium via IV during neurotoxic chemotherapy cycles has been evaluated for its effect on the prevention of peripheral neuropathy. It has been thought that acute neuropathic symptoms may be a result of certain chemotherapy agents bonding to calcium. Some neurotoxic agents also may result in hypomagnesemia. Infusion of calcium gluconate and magnesium sulfate immediately before and after chemotherapy administration has been evaluated for an effect in the prevention of peripheral neuropathy.
Calcium Aluminosilicate Clay
Calcium aluminosilicate clay is a compound of aluminosilicate and calcium ions that may absorb chemotherapeutic drugs and metabolites as well as inflammatory proteins. This may minimize radiation-induced damage to the intestinal epithelium and radiation-induced diarrhea.
Calcitonin
Calcitonin is a synthetic hormone, given as an injection, and a naturally occurring hormone in humans that is involved in calcium regulation and phosphate metabolism. Sometimes calcitonin is also used in the treatment of Paget disease, osteoporosis, and other benign bone diseases.
Buspirone
Buspirone is a type of anxiolytic psychotropic drug that has been used to treat anxiety and symptoms of anxiety.
Bupropion
Bupropion is used in the treatment of depression, as well as for seasonal affective disorder and smoking cessation. Bupropion is an antidepressant; it increases certain types of activity in the brain. Bupropion is available as a tablet and a sustained-release or extended-release tablet to take by mouth. Bupropion has been examined for effectiveness in the management of cancer-related fatigue and hot flashes.
Budesonide
Budesonide is used in treating Crohn's disease. It is a corticosteroid that decreases inflammation in the digestive tract of people who have Crohn’s disease to reduce inflammation and associated diarrhea. Budesonide is available as a capsule to take by mouth. It has been examined for its effect in treating chemotherapy-associated diarrhea.
Bryophyllum pinnatum
Bryophyllum pinnatum is a perennial herb that has been used in folklore medicine in several countries. This herb contains a wide range of chemical compounds such as alkaloids, flavonoids, steroids, lipids, and organic acids. Various plant extracts have central nervous system depression, analgesia, antimicrobial, anti-inflammatory, and sedative effects. Bryophyllum pinnatum has been studied for its effect on sleep-wake disturbances among patients with cancer.
BRAT Diet
The BRAT diet is a bland food diet consisting of bananas, rice, applesauce, and toast that may be recommended to adults and children for an upset stomach and diarrhea. The BRAT diet has been suggested for the management of diarrhea in patients with chemotherapy-induced diarrhea.
Bone-Modifying Agents
Bone-modifying agents include a variety of medications and therapeutic agents that prevent or treat damage from bone metastases in patients with cancer. The primary purpose of these agents is prevention of skeletal events, such as pathologic fracture, spinal cord compression, and hypercalcemia. In addition, bone-modifying agents may affect chronic pain from bone metastases. Bisphosphonates, denosumab, pamidronate, and zoledronic acid are examples of bone-modifying agents.