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Table of Contents
PICO questions
Search strategies
Evidence risk of bias figure
Evidence Profiles
Bowel regimen and lifestyle education vs. lifestyle education for opioid-induced constipation
Osmotic PEG and lifestyle education vs. lifestyle education for opioid-induced constipation
Methylnaltrexone (subcutaneous or oral) and bowel regimen vs. bowel regimen for opioid-induced constipation
Naldemedine (0.2 mg) and bowel regimen vs. bowel regimen for opioid-induced constipation
Naloxegol and bowel regimen vs. bowel regimen for opioid-induced constipation
Lubiprostone and bowel regimen vs. bowel regimen for opioid-induced constipation
Linaclotide and bowel regimen vs. bowel regimen for opioid-induced constipation
Prucalopride and bowel regimen vs. bowel regimen for opioid-induced constipation
Osmotic or stimulant laxatives and lifestyle education vs. lifestyle education for non-opioid-related constipation
Acupuncture and lifestyle education vs. lifestyle education for non-opioid-related constipation
Electroacupuncture and lifestyle education vs. lifestyle education for non-opioid-related constipation
Forest plots
Laxatives—Bowel movement frequency
Laxatives—Adverse events leading to treatment discontinuation
Naldemedine—Spontaneous Bowel Movements (SBMs)
Naldemedine—Adverse events leading to treatment discontinuation
Acupuncture—Bristol Stool Form Scale
Acupuncture—Adverse events
Acupuncture—Development of constipation
Characteristics of included studies
References
Online Exclusive, ONS Guidelines Article